Enhanced delivery of PEAL nanoparticles with ultrasound targeted microbubble destruction mediated siRNA transfection in human MCF-7/S and MCF-7/ADR cells in vitro

Enhanced delivery of PEAL nanoparticles with ultrasound targeted microbubble destruction mediated siRNA transfection in human MCF-7/S and MCF-7/ADR cells in vitro

The gene knockdown activity of small interfering RNA (siRNA) has led to their use as potential therapeutics for a variety of diseases. However, successful gene therapy requires safe and efficient delivery systems. In this study, we choose mPEG-PLGA-PLL nanoparticles (PEAL NPs) with ultrasound target...

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Bibliographic Details
Main Authors: Teng, Yanwei, Bai, Min, Sun, Ying, Wang, Qi, Li, Fan, Xing, Jinfang, Du, Lianfang, Gong, Tao, Duan, Yourong
Format: Online
Language:English
Published: Dove Medical Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556292/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556292/

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