Genetic polymorphisms of PAI-1 and PAR-1 are associated with acute normal tissue toxicity in Chinese rectal cancer patients treated with pelvic radiotherapy

Genetic polymorphisms of PAI-1 and PAR-1 are associated with acute normal tissue toxicity in Chinese rectal cancer patients treated with pelvic radiotherapy

Plasminogen activator inhibitor type 1 (PAI-1) and protease-activated receptor-1 (PAR-1) are crucial mediators of the intestinal microenvironment and are involved in radiation-induced acute and chronic injury. To evaluate whether genetic polymorphisms of PAI-1 and PAR-1 were predictors of radiation-...

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Bibliographic Details
Main Authors: Zhang, Hui, Wang, Mengyun, Shi, Tingyan, Shen, Lijun, Zhu, Ji, Sun, Menghong, Deng, Yun, Liang, Liping, Li, Guichao, Wu, Yongxin, Fan, Ming, Wei, Qingyi, Zhang, Zhen
Format: Online
Language:English
Published: Dove Medical Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556037/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556037/

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