Genetic Regulation of Dna2 Localization During the DNA Damage Response

DNA damage response pathways are crucial for protecting genome stability in all eukaryotes. Saccharomyces cerevisiae Dna2 has both helicase and nuclease activities that are essential for Okazaki fragment maturation, and Dna2 is involved in long-range DNA end resection at double-strand breaks. Dna2 f...

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Bibliographic Details
Main Authors: Yimit, Askar, Riffle, Michael, Brown, Grant W.
Format: Online
Language:English
Published: Genetics Society of America 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555230/