Mild Caloric Restriction Decreases Insulin Requirements in Patients With Type 2 Diabetes and Severe Insulin Resistance

Type 2 diabetes (T2D) affects ∼10% of the US population, a subset of whom have severe insulin resistance (SIR) (>200 units/d). Treatment of these patients with high-dose insulin presents logistical and compliance challenges. We hypothesized that mild caloric restriction would reduce insulin requi...

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Bibliographic Details
Main Authors: Meehan, Cristina Adelia, Cochran, Elaine, Mattingly, Megan, Gorden, Phillip, Brown, Rebecca J.
Format: Online
Language:English
Published: Wolters Kluwer Health 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554137/