Attenuation of Cerebral Ischemic Injury in Smad1 Deficient Mice

Stroke results in brain tissue damage from ischemia and oxidative stress. Molecular regulators of the protective versus deleterious cellular responses after cerebral ischemia remain to be identified. Here, we show that deletion of Smad1, a conserved transcription factor that mediates canonical bone...

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Bibliographic Details
Main Authors: Wong, Jamie K., Chen, Lei, Huang, Yong, Sehba, Fatima A., Friedel, Roland H., Zou, Hongyan
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552810/