Intermediate Tyrosyl Radical and Amyloid Structure in Peroxide-Activated Cytoglobin

We characterized the peroxidase mechanism of recombinant rat brain cytoglobin (Cygb) challenged by hydrogen peroxide, tert-butylhydroperoxide and by cumene hydroperoxide. The peroxidase mechanism of Cygb is similar to that of myoglobin. Cygb challenged by hydrogen peroxide is converted to a Fe4+ oxo...

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Bibliographic Details
Main Authors: Ferreira, Juliana C., Marcondes, Marcelo F., Icimoto, Marcelo Y., Cardoso, Thyago H. S., Tofanello, Aryane, Pessoto, Felipe S., Miranda, Erica G. A., Prieto, Tatiana, Nascimento, Otaciro R., Oliveira, Vitor, Nantes, Iseli L.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552303/