pH-Driven Polymorphism of Insulin Amyloid-Like Fibrils

Prions are infective proteins, which can self-assemble into different strain conformations, leading to different disease phenotypes. An increasing number of studies suggest that prion-like self-propagation may be a common feature of amyloid-like structures. Thus it is important to unravel every poss...

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Bibliographic Details
Main Authors: Sneideris, Tomas, Darguzis, Domantas, Botyriute, Akvile, Grigaliunas, Martynas, Winter, Roland, Smirnovas, Vytautas
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551895/