HUMAN DEFINITIVE HAEMOGENIC ENDOTHELIUM AND ARTERIAL VASCULAR ENDOTHELIUM REPRESENT DISTINCT LINEAGES

The generation of haematopoietic stem cells (HSCs) from human pluripotent stem cells (hPSCs) will depend on the accurate recapitulation of embryonic haematopoiesis. In the early embryo, HSCs develop from the haemogenic endothelium (HE) and are specified in a Notch-dependent manner through a process...

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Bibliographic Details
Main Authors: Ditadi, Andrea, Sturgeon, Christopher M., Tober, Joanna, Awong, Geneve, Kennedy, Marion, Phillips, Amanda, Azzola, Lisa, Ng, Elizabeth S., Stanley, Edouard, French, Deborah L., Cheng, Xin, Gadue, Paul, Speck, Nancy, Elefanty, Andrew G., Keller, Gordon
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551438/