The substrate matters in the Raman spectroscopy analysis of cells

Raman spectroscopy is a powerful analytical method that allows deposited and/or immobilized cells to be evaluated without complex sample preparation or labeling. However, a main limitation of Raman spectroscopy in cell analysis is the extremely weak Raman intensity that results in low signal to nois...

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Bibliographic Details
Main Authors: Mikoliunaite, Lina, Rodriguez, Raul D., Sheremet, Evgeniya, Kolchuzhin, Vladimir, Mehner, Jan, Ramanavicius, Arunas, Zahn, Dietrich R.T.
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550836/