Interleukin 21 Controls mRNA and MicroRNA Expression in CD40-Activated Chronic Lymphocytic Leukemia Cells

Several factors support CLL cell survival in the microenvironment. Under different experimental conditions, IL21 can either induce apoptosis or promote CLL cell survival. To investigate mechanisms involved in the effects of IL21, we studied the ability of IL21 to modulate gene and miRNA expressions...

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Bibliographic Details
Main Authors: De Cecco, Loris, Capaia, Matteo, Zupo, Simona, Cutrona, Giovanna, Matis, Serena, Brizzolara, Antonella, Orengo, Anna Maria, Croce, Michela, Marchesi, Edoardo, Ferrarini, Manlio, Canevari, Silvana, Ferrini, Silvano
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549109/