Perinatally administered losartan augments renal ACE2 expression but not cardiac or renal Mas receptor in spontaneously hypertensive rats

Perinatally administered losartan augments renal ACE2 expression but not cardiac or renal Mas receptor in spontaneously hypertensive rats

Since the identification of the alternative angiotensin converting enzyme (ACE)2/Ang-(1-7)/Mas receptor axis, renin-angiotensin system (RAS) is a new complex target for a pharmacological intervention. We investigated the expression of RAS components in the heart and kidney during the development of...

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Main Authors: Klimas, Jan, Olvedy, Michael, Ochodnicka-Mackovicova, Katarina, Kruzliak, Peter, Cacanyiova, Sona, Kristek, Frantisek, Krenek, Peter, Ochodnicky, Peter
Format: Online
Language:English
Published: John Wiley & Sons, Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549047/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549047/

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