Kindlin-3–mediated integrin adhesion is dispensable for quiescent but essential for activated hematopoietic stem cells

Kindlin-3–mediated integrin adhesion is dispensable for quiescent but essential for activated hematopoietic stem cells

Ruppert et al. report that Kindlin-3–mediated integrin activation controls homing of hematopoietic stem cells (HSCs) to the bone marrow (BM) and the retention of activated, but not quiescent, HSCs in the BM niche.

Bibliographic Details
Main Authors: Ruppert, Raphael, Moser, Markus, Sperandio, Markus, Rognoni, Emanuel, Orban, Martin, Liu, Wen-Hsin, Schulz, Ansgar S., Oostendorp, Robert A.J., Massberg, Steffen, Fässler, Reinhard
Format: Online
Language:English
Published: The Rockefeller University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548061/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548061/

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