Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts

Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts

In this study, we show that the transmembrane glycoprotein Trop-2 is up-regulated in human prostate cancer (PCa) with extracapsular extension (stages pT3/pT4) as compared to organ-confined (stage pT2) PCa. Consistent with this evidence, Trop-2 expression is found to be increased in metastatic prosta...

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Bibliographic Details
Main Authors: Trerotola, Marco, Ganguly, Kirat K., Fazli, Ladan, Fedele, Carmine, Lu, Huimin, Dutta, Anindita, Liu, Qin, De Angelis, Tiziana, Riddell, Luke W., Riobo, Natalia A., Gleave, Martin E., Zoubeidi, Amina, Pestell, Richard G., Altieri, Dario C., Languino, Lucia R.
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546469/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546469/

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