Enhanced oral bioavailability of vancomycin in rats treated with long-term parenteral nutrition

Enhanced oral bioavailability of vancomycin in rats treated with long-term parenteral nutrition

Long-term parenteral nutrition (PN) can induce intestinal atrophy, leading to a loss of epithelial integrity in the small intestines. This change may alter the intestinal permeability of vancomycin (VCM), a non-absorbable antibiotic. The aim of the present study was to investigate the effect of PN o...

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Bibliographic Details
Main Authors: Fukushima, Keizo, Okada, Akira, Hayashi, Yoriko, Ichikawa, Hideki, Nishimura, Asako, Shibata, Nobuhito, Sugioka, Nobuyuki
Format: Online
Language:English
Published: Springer International Publishing 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546118/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546118/

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