Generation of Naïve Bovine Induced Pluripotent Stem Cells Using PiggyBac Transposition of Doxycycline-Inducible Transcription Factors

Generation of pluripotent stem cells (PSCs) in large domestic animals has achieved only limited success; most of the PSCs obtained to date have been classified as primed PSCs, which possess very little capacity to produce chimeric offspring. By contrast, mouse PSCs have been classified as naïve PSCs...

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Bibliographic Details
Main Authors: Kawaguchi, Takamasa, Tsukiyama, Tomoyuki, Kimura, Koji, Matsuyama, Shuichi, Minami, Naojiro, Yamada, Masayasu, Imai, Hiroshi
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544884/