Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection

Mucosal damage to the gastrointestinal (GI) tract with resulting microbial translocation is hypothesized to significantly contribute to the heightened and persistent chronic inflammation and immune activation characteristic to HIV infection. Here we employ a non-human primate model of chemically ind...

Full description

Bibliographic Details
Main Authors: Hao, Xing Pei, Lucero, Carissa M., Turkbey, Baris, Bernardo, Marcelino L., Morcock, David R., Deleage, Claire, Trubey, Charles M., Smedley, Jeremy, Klatt, Nichole R., Giavedoni, Luis D., Kristoff, Jan, Xu, Amy, Del Prete, Gregory Q., Keele, Brandon F., Rao, Srinivas S., Alvord, W. Gregory, Choyke, Peter L., Lifson, Jeffrey D., Brenchley, Jason M., Apetrei, Cristian, Pandrea, Ivona, Estes, Jacob D.
Format: Online
Language:English
Published: Nature Pub. Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544774/