Variable Glutamine-Rich Repeats Modulate Transcription Factor Activity

Variable Glutamine-Rich Repeats Modulate Transcription Factor Activity

Excessive expansions of glutamine (Q)-rich repeats in various human proteins are known to result in severe neurodegenerative disorders such as Huntington’s disease and several ataxias. However, the physiological role of these repeats and the consequences of more moderate repeat variation remain unkn...

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Bibliographic Details
Main Authors: Gemayel, Rita, Chavali, Sreenivas, Pougach, Ksenia, Legendre, Matthieu, Zhu, Bo, Boeynaems, Steven, van der Zande, Elisa, Gevaert, Kris, Rousseau, Frederic, Schymkowitz, Joost, Babu, M. Madan, Verstrepen, Kevin J.
Format: Online
Language:English
Published: Cell Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543046/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543046/

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