Metabolic Syndrome Abolishes Glucagon-Like Peptide 1 Receptor Agonist Stimulation of SERCA in Coronary Smooth Muscle

Metabolic syndrome (MetS) doubles the risk of adverse cardiovascular events. Glucagon-like peptide 1 (GLP-1) receptor agonists induce weight loss, increase insulin secretion, and improve glucose tolerance. Studies in healthy animals suggest cardioprotective properties of GLP-1 receptor agonists, per...

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Bibliographic Details
Main Authors: Dineen, Stacey L., McKenney, Mikaela L., Bell, Lauren N., Fullenkamp, Allison M., Schultz, Kyle A., Alloosh, Mouhamad, Chalasani, Naga, Sturek, Michael
Format: Online
Language:English
Published: American Diabetes Association 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542436/