Id2 deletion attenuates Apc-deficient ileal tumor formation

The expression level of inhibitor of DNA binding 2 (Id2) is increased in colorectal carcinomas and is positively correlated with poor prognosis. However, the functional significance of Id2 in intestinal tumorigenesis has not been fully defined using genetic approaches. Here, we show that Id2 promote...

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Bibliographic Details
Main Authors: Biyajima, Kyoko, Kakizaki, Fumihiko, Shen, Xiaodong, Mori, Kentaro, Sugai, Manabu, Taketo, M. Mark, Yokota, Yoshifumi
Format: Online
Language:English
Published: The Company of Biologists 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542283/