An Alternative Terminal Step of the General Secretory Pathway in Staphylococcus aureus

Type I signal peptidase (SPase) is essential for viability in wild-type bacteria because the terminal step of the bacterial general secretory pathway requires its proteolytic activity to release proteins from their membrane-bound N-terminal leader sequences after translocation across the cytoplasmic...

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Bibliographic Details
Main Authors: Craney, Arryn, Dix, Melissa M., Adhikary, Ramkrishna, Cravatt, Benjamin F., Romesberg, Floyd E.
Format: Online
Language:English
Published: American Society of Microbiology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542188/