Cellular neurothekeoma: case report and its (un) relation with nerve sheath myxoma*
Neurothekeoma is an uncommon, benign neoplasm presenting in young adults, primarily on the head and neck. It was initially related to nerve sheath myxoma but with the advent of immunohistochemistry, new insights into its cellular differentiation and origin have emerged, unlinking Neurothekeoma and n...
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Sociedade Brasileira de Dermatologia
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540536/ |
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pubmed-45405362015-08-20 Cellular neurothekeoma: case report and its (un) relation with nerve sheath myxoma* Navarrete-Dechent, Cristián Curi-Tuma, Maximiliano Marín, Celeste González, Sergio Sandoval-Osses, Mauricio Case Report Neurothekeoma is an uncommon, benign neoplasm presenting in young adults, primarily on the head and neck. It was initially related to nerve sheath myxoma but with the advent of immunohistochemistry, new insights into its cellular differentiation and origin have emerged, unlinking Neurothekeoma and nerve sheath myxoma. Herein we describe a 19-year-old male who had had a frontal, fl esh-colored, asymptomatic papule for 2 years. Histology showed a dermal fusocellular-spindle cell tumor, including an eosinophilic cytoplasm with mild cellular pleomorphism and moderately dense fi brous stroma. IHQ was positive for CD10 and negative for S100 and Claudin-1. These fi ndings were compatible with cellular Neurothekeoma. The lesion was completely extirpated and at the 6-month follow-up, the patient was asymptomatic and had experienced no recurrences. Sociedade Brasileira de Dermatologia 2015 /pmc/articles/PMC4540536/ /pubmed/26312702 http://dx.doi.org/10.1590/abd1806-4841.20153402 Text en © 2015 by Anais Brasileiros de Dermatologia http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Navarrete-Dechent, Cristián Curi-Tuma, Maximiliano Marín, Celeste González, Sergio Sandoval-Osses, Mauricio |
| spellingShingle |
Navarrete-Dechent, Cristián Curi-Tuma, Maximiliano Marín, Celeste González, Sergio Sandoval-Osses, Mauricio Cellular neurothekeoma: case report and its (un) relation with nerve sheath myxoma* |
| author_facet |
Navarrete-Dechent, Cristián Curi-Tuma, Maximiliano Marín, Celeste González, Sergio Sandoval-Osses, Mauricio |
| author_sort |
Navarrete-Dechent, Cristián |
| title |
Cellular neurothekeoma: case report and its (un) relation with nerve
sheath myxoma* |
| title_short |
Cellular neurothekeoma: case report and its (un) relation with nerve
sheath myxoma* |
| title_full |
Cellular neurothekeoma: case report and its (un) relation with nerve
sheath myxoma* |
| title_fullStr |
Cellular neurothekeoma: case report and its (un) relation with nerve
sheath myxoma* |
| title_full_unstemmed |
Cellular neurothekeoma: case report and its (un) relation with nerve
sheath myxoma* |
| title_sort |
cellular neurothekeoma: case report and its (un) relation with nerve
sheath myxoma* |
| description |
Neurothekeoma is an uncommon, benign neoplasm presenting in young adults, primarily
on the head and neck. It was initially related to nerve sheath myxoma but with the
advent of immunohistochemistry, new insights into its cellular differentiation and
origin have emerged, unlinking Neurothekeoma and nerve sheath myxoma. Herein we
describe a 19-year-old male who had had a frontal, fl esh-colored, asymptomatic
papule for 2 years. Histology showed a dermal fusocellular-spindle cell tumor,
including an eosinophilic cytoplasm with mild cellular pleomorphism and moderately
dense fi brous stroma. IHQ was positive for CD10 and negative for S100 and Claudin-1.
These fi ndings were compatible with cellular Neurothekeoma. The lesion was
completely extirpated and at the 6-month follow-up, the patient was asymptomatic and
had experienced no recurrences. |
| publisher |
Sociedade Brasileira de Dermatologia |
| publishDate |
2015 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540536/ |
| _version_ |
1613260993902673920 |