Cutaneous metastases from gastric adenocarcinoma 15 years after curative gastrectomy*

We report the case of a 38-year-old man, who developed cutaneous metastases in the left inguinal groove 15 years after curative gastrectomy for advanced gastric adenocarcinoma. Histopathologic examination revealed poorly differentiated adenocarcinoma cells. They were stained positive for villin, CDX...

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Main Authors:	Liu, Fang, Yan, Wen Liang, Liu, Haibo, Zhang, Min, Sang, Hong
Format:	Online
Language:	English
Published:	Sociedade Brasileira de Dermatologia 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540506/

id	pubmed-4540506
recordtype	oai_dc
spelling	pubmed-45405062015-08-20 Cutaneous metastases from gastric adenocarcinoma 15 years after curative gastrectomy* Liu, Fang Yan, Wen Liang Liu, Haibo Zhang, Min Sang, Hong Case Report We report the case of a 38-year-old man, who developed cutaneous metastases in the left inguinal groove 15 years after curative gastrectomy for advanced gastric adenocarcinoma. Histopathologic examination revealed poorly differentiated adenocarcinoma cells. They were stained positive for villin, CDX-2, CKpan (AE1/ AE3), CEA, CK8/18, CK19, CK7, EMA, Ki-67 (50%), and negative for S-100, CK20, CD34, GCDFP-15 and TTF-1. The patient underwent local excision, after the presence of other metastases was excluded. Nevertheless, local recurrence developed at the surgical bed one year later and PET/CT revealed metastases to lymph nodes, bone and skin. He died 2 years after the appearance of cutaneous metastases. We have reviewed the literature and described the immunohistochemical characteristics of cutaneous metastases from gastric adenocarcinoma. Sociedade Brasileira de Dermatologia 2015 /pmc/articles/PMC4540506/ /pubmed/26312672 http://dx.doi.org/10.1590/abd1806-4841.20153829 Text en © 2015 by Anais Brasileiros de Dermatologia http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Liu, Fang Yan, Wen Liang Liu, Haibo Zhang, Min Sang, Hong
spellingShingle	Liu, Fang Yan, Wen Liang Liu, Haibo Zhang, Min Sang, Hong Cutaneous metastases from gastric adenocarcinoma 15 years after curative gastrectomy*
author_facet	Liu, Fang Yan, Wen Liang Liu, Haibo Zhang, Min Sang, Hong
author_sort	Liu, Fang
title	Cutaneous metastases from gastric adenocarcinoma 15 years after curative gastrectomy*
title_short	Cutaneous metastases from gastric adenocarcinoma 15 years after curative gastrectomy*
title_full	Cutaneous metastases from gastric adenocarcinoma 15 years after curative gastrectomy*
title_fullStr	Cutaneous metastases from gastric adenocarcinoma 15 years after curative gastrectomy*
title_full_unstemmed	Cutaneous metastases from gastric adenocarcinoma 15 years after curative gastrectomy*
title_sort	cutaneous metastases from gastric adenocarcinoma 15 years after curative gastrectomy*
description	We report the case of a 38-year-old man, who developed cutaneous metastases in the left inguinal groove 15 years after curative gastrectomy for advanced gastric adenocarcinoma. Histopathologic examination revealed poorly differentiated adenocarcinoma cells. They were stained positive for villin, CDX-2, CKpan (AE1/ AE3), CEA, CK8/18, CK19, CK7, EMA, Ki-67 (50%), and negative for S-100, CK20, CD34, GCDFP-15 and TTF-1. The patient underwent local excision, after the presence of other metastases was excluded. Nevertheless, local recurrence developed at the surgical bed one year later and PET/CT revealed metastases to lymph nodes, bone and skin. He died 2 years after the appearance of cutaneous metastases. We have reviewed the literature and described the immunohistochemical characteristics of cutaneous metastases from gastric adenocarcinoma.
publisher	Sociedade Brasileira de Dermatologia
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540506/
_version_	1613260975765454848

Cutaneous metastases from gastric adenocarcinoma 15 years after curative gastrectomy*

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