Alginate as a protease inhibitor in vitro and in a model gut system; selective inhibition of pepsin but not trypsin
•Alginate inhibits proteolytic activity of pepsin but not trypsin.•Level of pepsin inhibition correlates with alginate F[M].•An in vitro model gut system was used to model alginate inhibition of proteolysis.•Proteolysis inhibited in gastric phase of digestion, but not small intestinal phase.•pH depe...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Elsevier Applied Science Publishers
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539341/ |