Moyamoya disease susceptibility gene RNF213 links inflammatory and angiogenic signals in endothelial cells

Moyamoya disease susceptibility gene RNF213 links inflammatory and angiogenic signals in endothelial cells

Moyamoya disease (MMD) is a cerebrovascular disorder characterized by occlusive lesions of the circle of Willis. To date, both environmental and genetic factors have been implicated for pathogenesis of MMD. Allelic variations in RNF213 are known to confer the risk of MMD; however, functional roles o...

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Bibliographic Details
Main Authors: Ohkubo, Kazuhiro, Sakai, Yasunari, Inoue, Hirosuke, Akamine, Satoshi, Ishizaki, Yoshito, Matsushita, Yuki, Sanefuji, Masafumi, Torisu, Hiroyuki, Ihara, Kenji, Sardiello, Marco, Hara, Toshiro
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538604/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538604/

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