In Silico-Based High-Throughput Screen for Discovery of Novel Combinations for Tuberculosis Treatment

In Silico-Based High-Throughput Screen for Discovery of Novel Combinations for Tuberculosis Treatment

There are currently 18 drug classes for the treatment of tuberculosis, including those in the development pipeline. An in silico simulation enabled combing the innumerably large search space to derive multidrug combinations. Through the use of ordinary differential equations (ODE), we constructed an...

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Bibliographic Details
Main Authors: Singh, Ragini, Ramachandran, Vasanthi, Shandil, Radha, Sharma, Sreevalli, Khandelwal, Swati, Karmarkar, Malancha, Kumar, Naveen, Solapure, Suresh, Saralaya, Ramanatha, Nanduri, Robert, Panduga, Vijender, Reddy, Jitendar, Prabhakar, K. R., Rajagopalan, Swaminathan, Rao, Narasimha, Narayanan, Shridhar, Anandkumar, Anand, Balasubramanian, V., Datta, Santanu
Format: Online
Language:English
Published: American Society for Microbiology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538536/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538536/

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