A human laterality disorder associated with a homozygous WDR16 deletion

The laterality in the embryo is determined by left-right asymmetric gene expression driven by the flow of extraembryonic fluid, which is maintained by the rotary movement of monocilia on the nodal cells. Defects manifest by abnormal formation and arrangement of visceral organs. The genetic etiology...

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Bibliographic Details
Main Authors: Ta-Shma, Asaf, Perles, Zeev, Yaacov, Barak, Werner, Marion, Frumkin, Ayala, Rein, Azaria JJT, Elpeleg, Orly
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538206/