Targeted sequencing with enrichment PCR: a novel diagnostic method for the detection of EGFR mutations

Epidermal growth factor receptor (EGFR) is an important mediator of tumor cell survival and proliferation. The detection of EGFR mutations can predict prognoses and indicate when treatment with EGFR tyrosine kinase inhibitors should be used. As such, the development of highly sensitive methods for d...

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Bibliographic Details
Main Authors: Kang, Suki, Kim, Baek Gil, Han, Hyun Ho, Lee, Joo Hyun, Kim, Ji Eun, Shim, Hyo Sup, Cho, Nam Hoon
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537046/