A molecular tweezer antagonizes seminal amyloids and HIV infection

A molecular tweezer antagonizes seminal amyloids and HIV infection

Semen is the main vector for HIV transmission and contains amyloid fibrils that enhance viral infection. Available microbicides that target viral components have proven largely ineffective in preventing sexual virus transmission. In this study, we establish that CLR01, a ‘molecular tweezer’ specific...

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Bibliographic Details
Main Authors: Lump, Edina, Castellano, Laura M, Meier, Christoph, Seeliger, Janine, Erwin, Nelli, Sperlich, Benjamin, Stürzel, Christina M, Usmani, Shariq, Hammond, Rebecca M, von Einem, Jens, Gerold, Gisa, Kreppel, Florian, Bravo-Rodriguez, Kenny, Pietschmann, Thomas, Holmes, Veronica M, Palesch, David, Zirafi, Onofrio, Weissman, Drew, Sowislok, Andrea, Wettig, Burkhard, Heid, Christian, Kirchhoff, Frank, Weil, Tanja, Klärner, Frank-Gerrit, Schrader, Thomas, Bitan, Gal, Sanchez-Garcia, Elsa, Winter, Roland, Shorter, James, Münch, Jan
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536748/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536748/

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