Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies

Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies

The broadly neutralizing HIV monoclonal antibodies (bnMAbs) PG9, PG16, PGT151, and PGT152 have been shown earlier to occasionally display an unusual virus neutralization profile with a non-sigmoidal slope and a plateau at <100% neutralization. In the current study, we were interested in determini...

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Bibliographic Details
Main Authors: McCoy, Laura E., Falkowska, Emilia, Doores, Katie J., Le, Khoa, Sok, Devin, van Gils, Marit J., Euler, Zelda, Burger, Judith A., Seaman, Michael S., Sanders, Rogier W., Schuitemaker, Hanneke, Poignard, Pascal, Wrin, Terri, Burton, Dennis R.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534392/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534392/

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