STIM1 accelerates cell senescence in a remodeled microenvironment but enhances the epithelial-to-mesenchymal transition in prostate cancer

STIM1 accelerates cell senescence in a remodeled microenvironment but enhances the epithelial-to-mesenchymal transition in prostate cancer

The importance of store-operated Ca2+ entry (SOCE) and the role of its key molecular regulators, STIM1 and ORAI1, in the development of cancer are emerging. Here, we report an unexpected dual function of SOCE in prostate cancer progression by revealing a decrease in the expression of STIM1 in human...

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Bibliographic Details
Main Authors: Xu, Yingxi, Zhang, Shu, Niu, Haiying, Ye, Yujie, Hu, Fen, Chen, Si, Li, Xuefei, Luo, Xiaohe, Jiang, Shan, Liu, Yanhua, Chen, Yanan, Li, Junying, Xiang, Rong, Li, Na
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530453/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530453/

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