MUC1-C ACTIVATES THE TAK1 INFLAMMATORY PATHWAY IN COLON CANCER
The mucin 1 (MUC1) oncoprotein has been linked to the inflammatory response by promoting cytokine-mediated activation of the NF-κB pathway. The TGF-β-activated kinase 1 (TAK1) is an essential effector of proinflammatory NF-κB signaling that also regulates cancer cell survival. The present studies de...
Main Authors: | , , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530107/ |