MUC1-C ACTIVATES THE TAK1 INFLAMMATORY PATHWAY IN COLON CANCER

The mucin 1 (MUC1) oncoprotein has been linked to the inflammatory response by promoting cytokine-mediated activation of the NF-κB pathway. The TGF-β-activated kinase 1 (TAK1) is an essential effector of proinflammatory NF-κB signaling that also regulates cancer cell survival. The present studies de...

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Bibliographic Details
Main Authors: Takahashi, Hidekazu, Jin, Caining, Rajabi, Hasan, Pitroda, Sean, Alam, Maroof, Ahmad, Rehan, Raina, Deepak, Hasegawa, Masanori, Suzuki, Yozo, Tagde, Ashujit, Bronson, Roderick T., Weichselbaum, Ralph, Kufe, Donald
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530107/