NO to cancer: The complex and multifaceted role of nitric oxide and the epigenetic nitric oxide donor, RRx-001☆

The endogenous mediator of vasodilation, nitric oxide (NO), has been shown to be a potent radiosensitizer. However, the underlying mode of action for its role as a radiosensitizer – while not entirely understood – is believed to arise from increased tumor blood flow, effects on cellular respiration,...

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Bibliographic Details
Main Authors: Scicinski, Jan, Oronsky, Bryan, Ning, Shoucheng, Knox, Susan, Peehl, Donna, Kim, Michelle M., Langecker, Peter, Fanger, Gary
Format: Online
Language:English
Published: Elsevier 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529402/