Promotion of Erythropoietic Differentiation in Hematopoietic Stem Cells by SOCS3 Knock-Down

Suppressor of cytokine signaling 3 (SOCS3) plays an important role in mice fetal liver erythropoiesis, but the roles of SOCS3 in human hematopoietic stem cells (HSCs) have not been well investigated. In the present study, lentiviral small interference RNA expression vectors (shRNA) of SOCS3 were con...

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Bibliographic Details
Main Authors: Liu, Yu-xiao, Dong, Xing, Gong, Feng, Su, Ning, Li, Su-bo, Zhang, Hai-tao, Liu, Jia-ling, Xue, Jing-hui, Ji, Shou-ping, Zhang, Zhi–wen
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529111/