Use of Placental Membranes for the Treatment of Chronic Diabetic Foot Ulcers

Significance: Chronic diabetic foot ulcers (DFUs) remain a challenge for physicians to treat. High mortality rates for DFU patients have pointed to the low effectiveness of standard care and lack of quality wound care products. The composition (collagen-rich tissue matrix and endogenous growth facto...

Full description

Bibliographic Details
Main Authors: Brantley, Jonathan N., Verla, Thomas D.
Format: Online
Language:English
Published: Mary Ann Liebert, Inc. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529081/
id pubmed-4529081
recordtype oai_dc
spelling pubmed-45290812015-09-03 Use of Placental Membranes for the Treatment of Chronic Diabetic Foot Ulcers Brantley, Jonathan N. Verla, Thomas D. Critical Review Significance: Chronic diabetic foot ulcers (DFUs) remain a challenge for physicians to treat. High mortality rates for DFU patients have pointed to the low effectiveness of standard care and lack of quality wound care products. The composition (collagen-rich tissue matrix and endogenous growth factors and cells) and functional properties (anti-inflammatory, anti-bacterial, and angiogenic) of placental membranes are uniquely suited to address the needs of chronic wounds. This led to the commercialization of placental membranes, which are now widely available to physicians as a new advanced wound treatment option. Mary Ann Liebert, Inc. 2015-09-01 /pmc/articles/PMC4529081/ /pubmed/26339533 http://dx.doi.org/10.1089/wound.2015.0634 Text en Copyright 2015, Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons Attribution Noncommercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Brantley, Jonathan N.
Verla, Thomas D.
spellingShingle Brantley, Jonathan N.
Verla, Thomas D.
Use of Placental Membranes for the Treatment of Chronic Diabetic Foot Ulcers
author_facet Brantley, Jonathan N.
Verla, Thomas D.
author_sort Brantley, Jonathan N.
title Use of Placental Membranes for the Treatment of Chronic Diabetic Foot Ulcers
title_short Use of Placental Membranes for the Treatment of Chronic Diabetic Foot Ulcers
title_full Use of Placental Membranes for the Treatment of Chronic Diabetic Foot Ulcers
title_fullStr Use of Placental Membranes for the Treatment of Chronic Diabetic Foot Ulcers
title_full_unstemmed Use of Placental Membranes for the Treatment of Chronic Diabetic Foot Ulcers
title_sort use of placental membranes for the treatment of chronic diabetic foot ulcers
description Significance: Chronic diabetic foot ulcers (DFUs) remain a challenge for physicians to treat. High mortality rates for DFU patients have pointed to the low effectiveness of standard care and lack of quality wound care products. The composition (collagen-rich tissue matrix and endogenous growth factors and cells) and functional properties (anti-inflammatory, anti-bacterial, and angiogenic) of placental membranes are uniquely suited to address the needs of chronic wounds. This led to the commercialization of placental membranes, which are now widely available to physicians as a new advanced wound treatment option.
publisher Mary Ann Liebert, Inc.
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529081/
_version_ 1613257035574411264