Use of Placental Membranes for the Treatment of Chronic Diabetic Foot Ulcers
Significance: Chronic diabetic foot ulcers (DFUs) remain a challenge for physicians to treat. High mortality rates for DFU patients have pointed to the low effectiveness of standard care and lack of quality wound care products. The composition (collagen-rich tissue matrix and endogenous growth facto...
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Mary Ann Liebert, Inc.
2015
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pubmed-45290812015-09-03 Use of Placental Membranes for the Treatment of Chronic Diabetic Foot Ulcers Brantley, Jonathan N. Verla, Thomas D. Critical Review Significance: Chronic diabetic foot ulcers (DFUs) remain a challenge for physicians to treat. High mortality rates for DFU patients have pointed to the low effectiveness of standard care and lack of quality wound care products. The composition (collagen-rich tissue matrix and endogenous growth factors and cells) and functional properties (anti-inflammatory, anti-bacterial, and angiogenic) of placental membranes are uniquely suited to address the needs of chronic wounds. This led to the commercialization of placental membranes, which are now widely available to physicians as a new advanced wound treatment option. Mary Ann Liebert, Inc. 2015-09-01 /pmc/articles/PMC4529081/ /pubmed/26339533 http://dx.doi.org/10.1089/wound.2015.0634 Text en Copyright 2015, Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons Attribution Noncommercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Brantley, Jonathan N. Verla, Thomas D. |
spellingShingle |
Brantley, Jonathan N. Verla, Thomas D. Use of Placental Membranes for the Treatment of Chronic Diabetic Foot Ulcers |
author_facet |
Brantley, Jonathan N. Verla, Thomas D. |
author_sort |
Brantley, Jonathan N. |
title |
Use of Placental Membranes for the Treatment of Chronic Diabetic Foot Ulcers |
title_short |
Use of Placental Membranes for the Treatment of Chronic Diabetic Foot Ulcers |
title_full |
Use of Placental Membranes for the Treatment of Chronic Diabetic Foot Ulcers |
title_fullStr |
Use of Placental Membranes for the Treatment of Chronic Diabetic Foot Ulcers |
title_full_unstemmed |
Use of Placental Membranes for the Treatment of Chronic Diabetic Foot Ulcers |
title_sort |
use of placental membranes for the treatment of chronic diabetic foot ulcers |
description |
Significance: Chronic diabetic foot ulcers (DFUs) remain a challenge for physicians to treat. High mortality rates for DFU patients have pointed to the low effectiveness of standard care and lack of quality wound care products. The composition (collagen-rich tissue matrix and endogenous growth factors and cells) and functional properties (anti-inflammatory, anti-bacterial, and angiogenic) of placental membranes are uniquely suited to address the needs of chronic wounds. This led to the commercialization of placental membranes, which are now widely available to physicians as a new advanced wound treatment option. |
publisher |
Mary Ann Liebert, Inc. |
publishDate |
2015 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529081/ |
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1613257035574411264 |