Leishmania infection modulates beta-1 integrin activation and alters the kinetics of monocyte spreading over fibronectin

Contact with Leishmania leads to a decreases in mononuclear phagocyte adherence to connective tissue. In this work, we studied the early stages of bond formation between VLA4 and fibronectin, measured the kinetics of membrane alignment and the monocyte cytoplasm spreading area over a fibronectin-coa...

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Bibliographic Details
Main Authors: Figueira, Cláudio Pereira, Carvalhal, Djalma Gomes Ferrão, Almeida, Rafaela Andrade, Hermida, Micely d’ El-Rei, Touchard, Dominique, Robert, Phillipe, Pierres, Anne, Bongrand, Pierre, dos-Santos, Washington LC
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528201/