Structure and vascular function of MEKK3–cerebral cavernous malformations 2 complex

Structure and vascular function of MEKK3–cerebral cavernous malformations 2 complex

Cerebral cavernous malformations 2 (CCM2) loss is associated with the familial form of CCM disease. The protein kinase MEKK3 (MAP3K3) is essential for embryonic angiogenesis in mice and interacts physically with CCM2, but how this interaction is mediated and its relevance to cerebral vasculature are...

Full description

Bibliographic Details
Main Authors: Fisher, Oriana S., Deng, Hanqiang, Liu, Dou, Zhang, Ya, Wei, Rong, Deng, Yong, Zhang, Fan, Louvi, Angeliki, Turk, Benjamin E., Boggon, Titus J., Su, Bing
Format: Online
Language:English
Published: Nature Pub. Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526114/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526114/

Similar Items