Defining the roles of arrestin2 and arrestin3 in vasoconstrictor receptor desensitization in hypertension
Prolonged vasoconstrictor-stimulated phospholipase C activity can induce arterial constriction, hypertension, and smooth muscle hypertrophy/hyperplasia. Arrestin proteins are recruited by agonist-occupied G protein-coupled receptors to terminate signaling and counteract changes in vascular tone. Her...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
American Physiological Society
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525080/ |