Hyperinvasive Meningococci Induce Intra-nuclear Cleavage of the NF-κB Protein p65/RelA by Meningococcal IgA Protease

Hyperinvasive Meningococci Induce Intra-nuclear Cleavage of the NF-κB Protein p65/RelA by Meningococcal IgA Protease

Differential modulation of NF-κB during meningococcal infection is critical in innate immune response to meningococcal disease. Non-invasive isolates of Neisseria meningitidis provoke a sustained NF-κB activation in epithelial cells. However, the hyperinvasive isolates of the ST-11 clonal complex (S...

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Bibliographic Details
Main Authors: Besbes, Anissa, Le Goff, Salomé, Antunes, Ana, Terrade, Aude, Hong, Eva, Giorgini, Dario, Taha, Muhamed-Kheir, Deghmane, Ala-Eddine
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524725/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524725/

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