Estimating the Fitness Effects of New Mutations in the Wild Yeast Saccharomyces paradoxus

The nature of selection acting on a population is in large measure determined by the distribution of fitness effects of new mutations. In this study, we use DNA sequences from four closely related clades of Saccharomyces paradoxus and Saccharomyces cerevisiae to identify and polarize new mutations a...

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Bibliographic Details
Main Authors: Koufopanou, Vassiliki, Lomas, Susan, Tsai, Isheng J., Burt, Austin
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524479/