Myogenic transcription factors regulate pro-metastatic miR-182

Approximately thirty percent of patients with soft-tissue sarcoma die from pulmonary metastases. The mechanisms that drive sarcoma metastasis are not well understood. Recently, we identified miR-182 as a driver of sarcoma metastasis in a primary mouse model of soft-tissue sarcoma. We also observed e...

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Bibliographic Details
Main Authors: Dodd, Rebecca D., Sachdeva, Mohit, Mito, Jeffrey K., Eward, William C., Brigman, Brian E., Ma, Yan, Dodd, Leslie, Kim, Youngbaek, Lev, Dina, Kirsch, David G.
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523886/