Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques

Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques

HIV-1 mucosal transmission begins with virus or virus-infected cells moving through mucus across mucosal epithelium to infect CD4+ T cells. Although broadly neutralizing antibodies (bnAbs) are the type of HIV-1 antibodies that are most likely protective, they are not induced with current vaccine can...

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Bibliographic Details
Main Authors: Santra, Sampa, Tomaras, Georgia D., Warrier, Ranjit, Nicely, Nathan I., Liao, Hua-Xin, Pollara, Justin, Liu, Pinghuang, Alam, S. Munir, Zhang, Ruijun, Cocklin, Sarah L., Shen, Xiaoying, Duffy, Ryan, Xia, Shi-Mao, Schutte, Robert J., Pemble IV, Charles W., Dennison, S. Moses, Li, Hui, Chao, Andrew, Vidnovic, Kora, Evans, Abbey, Klein, Katja, Kumar, Amit, Robinson, James, Landucci, Gary, Forthal, Donald N., Montefiori, David C., Kaewkungwal, Jaranit, Nitayaphan, Sorachai, Pitisuttithum, Punnee, Rerks-Ngarm, Supachai, Robb, Merlin L., Michael, Nelson L., Kim, Jerome H., Soderberg, Kelly A., Giorgi, Elena E., Blair, Lily, Korber, Bette T., Moog, Christiane, Shattock, Robin J., Letvin, Norman L., Schmitz, Joern E., Moody, M. A., Gao, Feng, Ferrari, Guido, Shaw, George M., Haynes, Barton F.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523205/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523205/

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