BCRP and P-gp relay overexpression in triple negative basal-like breast cancer cell line: a prospective role in resistance to Olaparib

BCRP and P-gp relay overexpression in triple negative basal-like breast cancer cell line: a prospective role in resistance to Olaparib

The triple negative basal-like (TNBL) breast carcinoma is an aggressive and unfavorable prognosis disease. Inhibitors of poly(ADP-ribose) polymerase such as Olaparib could represent a promising targeted therapy but their sensitivity against Multidrug Resistance proteins (MDR), which causes resistanc...

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Bibliographic Details
Main Authors: Dufour, Robin, Daumar, Pierre, Mounetou, Emmanuelle, Aubel, Corinne, Kwiatkowski, Fabrice, Abrial, Catherine, Vatoux, Catherine, Penault-Llorca, Frédérique, Bamdad, Mahchid
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522660/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522660/

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