Targeting the adaptive molecular landscape of castration-resistant prostate cancer
Castration and androgen receptor (AR) pathway inhibitors induce profound and sustained responses in advanced prostate cancer. However, the inevitable recurrence is associated with reactivation of the AR and progression to a more aggressive phenotype termed castration-resistant prostate cancer (CRPC)...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
John Wiley & Sons, Ltd
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520654/ |