Intratumoral and peritumoral post-irradiation changes, but not viable tumor tissue, may respond to bevacizumab in previously irradiated meningiomas

The efficacy of bevacizumab has not been determined for treatment-refractory meningiomas. We treated meningiomas with low-dose bevacizumab and compared the radiological responses of non-irradiated meningiomas with previously irradiated meningiomas. In addition, we assessed intraparenchymal radiation...

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Main Authors:	Furuse, Motomasa, Nonoguchi, Naosuke, Kawabata, Shinji, Miyata, Tomo, Toho, Taichiro, Kuroiwa, Toshihiko, Miyatake, Shin-Ichi
Format:	Online
Language:	English
Published:	BioMed Central 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520201/

id	pubmed-4520201
recordtype	oai_dc
spelling	pubmed-45202012015-07-31 Intratumoral and peritumoral post-irradiation changes, but not viable tumor tissue, may respond to bevacizumab in previously irradiated meningiomas Furuse, Motomasa Nonoguchi, Naosuke Kawabata, Shinji Miyata, Tomo Toho, Taichiro Kuroiwa, Toshihiko Miyatake, Shin-Ichi Case Report The efficacy of bevacizumab has not been determined for treatment-refractory meningiomas. We treated meningiomas with low-dose bevacizumab and compared the radiological responses of non-irradiated meningiomas with previously irradiated meningiomas. In addition, we assessed intraparenchymal radiation necrosis following bevacizumab treatment. BioMed Central 2015-07-30 /pmc/articles/PMC4520201/ /pubmed/26223253 http://dx.doi.org/10.1186/s13014-015-0446-0 Text en © Furuse et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Furuse, Motomasa Nonoguchi, Naosuke Kawabata, Shinji Miyata, Tomo Toho, Taichiro Kuroiwa, Toshihiko Miyatake, Shin-Ichi
spellingShingle	Furuse, Motomasa Nonoguchi, Naosuke Kawabata, Shinji Miyata, Tomo Toho, Taichiro Kuroiwa, Toshihiko Miyatake, Shin-Ichi Intratumoral and peritumoral post-irradiation changes, but not viable tumor tissue, may respond to bevacizumab in previously irradiated meningiomas
author_facet	Furuse, Motomasa Nonoguchi, Naosuke Kawabata, Shinji Miyata, Tomo Toho, Taichiro Kuroiwa, Toshihiko Miyatake, Shin-Ichi
author_sort	Furuse, Motomasa
title	Intratumoral and peritumoral post-irradiation changes, but not viable tumor tissue, may respond to bevacizumab in previously irradiated meningiomas
title_short	Intratumoral and peritumoral post-irradiation changes, but not viable tumor tissue, may respond to bevacizumab in previously irradiated meningiomas
title_full	Intratumoral and peritumoral post-irradiation changes, but not viable tumor tissue, may respond to bevacizumab in previously irradiated meningiomas
title_fullStr	Intratumoral and peritumoral post-irradiation changes, but not viable tumor tissue, may respond to bevacizumab in previously irradiated meningiomas
title_full_unstemmed	Intratumoral and peritumoral post-irradiation changes, but not viable tumor tissue, may respond to bevacizumab in previously irradiated meningiomas
title_sort	intratumoral and peritumoral post-irradiation changes, but not viable tumor tissue, may respond to bevacizumab in previously irradiated meningiomas
description	The efficacy of bevacizumab has not been determined for treatment-refractory meningiomas. We treated meningiomas with low-dose bevacizumab and compared the radiological responses of non-irradiated meningiomas with previously irradiated meningiomas. In addition, we assessed intraparenchymal radiation necrosis following bevacizumab treatment.
publisher	BioMed Central
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520201/
_version_	1613254163516358656

Intratumoral and peritumoral post-irradiation changes, but not viable tumor tissue, may respond to bevacizumab in previously irradiated meningiomas

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