Repression of arterial genes in hemogenic endothelium is sufficient for haematopoietic fate acquisition

Changes in cell fate and identity are essential for endothelial-to-haematopoietic transition (EHT), an embryonic process that generates the first adult populations of haematopoietic stem cells (HSCs) from hemogenic endothelial cells. Dissecting EHT regulation is a critical step towards the productio...

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Bibliographic Details
Main Authors: Lizama, Carlos O., Hawkins, John S., Schmitt, Christopher E., Bos, Frank L., Zape, Joan P., Cautivo, Kelly M., Borges Pinto, Hugo, Rhyner, Alexander M., Yu, Hui, Donohoe, Mary E., Wythe, Joshua D., Zovein, Ann C.
Format: Online
Language:English
Published: Nature Pub. Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519987/