Hypoxia Up-Regulates Galectin-3 in Mammary Tumor Progression and Metastasis

The tumor microenvironment encompasses several stressful conditions for cancer cells such as hypoxia, oxidative stress and pH alterations. Galectin-3, a well-studied member of the beta-galactoside-binding animal family of lectins has been implicated in multiple steps of metastasis as cell-cell and c...

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Bibliographic Details
Main Authors: de Oliveira, Joana T., Ribeiro, Cláudia, Barros, Rita, Gomes, Catarina, de Matos, Augusto J., Reis, Celso A., Rutteman, Gerard R., Gärtner, Fátima
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519331/