Immunogenicity of the Plasmodium falciparum PfEMP1-VarO Adhesin: Induction of Surface-Reactive and Rosette-Disrupting Antibodies to VarO Infected Erythrocytes

Immunogenicity of the Plasmodium falciparum PfEMP1-VarO Adhesin: Induction of Surface-Reactive and Rosette-Disrupting Antibodies to VarO Infected Erythrocytes

Adhesion of Plasmodium falciparum-infected red blood cells (iRBC) to human erythrocytes (i.e. rosetting) is associated with severe malaria. Rosetting results from interactions between a subset of variant PfEMP1 (Plasmodium falciparum erythrocyte membrane protein 1) adhesins and specific erythrocyte...

Full description

Bibliographic Details
Main Authors: Guillotte, Micheline, Juillerat, Alexandre, Igonet, Sébastien, Hessel, Audrey, Petres, Stéphane, Crublet, Elodie, Le Scanf, Cécile, Lewit-Bentley, Anita, Bentley, Graham A., Vigan-Womas, Inès, Mercereau-Puijalon, Odile
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519321/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519321/

Similar Items