Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation

Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation

Isoliensinine, liensinine and neferine are major bisbenzylisoquinoline alkaloids in the seed embryo of lotus (Nelumbo nucifera), and exhibit potential anti-cancer activity. Here, we explored the effects of these alkaloids on triple-negative breast cancer cells and found that among the three alkaloid...

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Bibliographic Details
Main Authors: Zhang, Xiyu, Wang, Xiyao, Wu, Tingting, Li, Boxuan, Liu, Tianqi, Wang, Rong, Liu, Qiao, Liu, Zhaojian, Gong, Yaoqin, Shao, Changshun
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518223/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518223/

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