The mediation of coronary calcification in the association between risk scores and cardiac troponin T elevation in healthy adults: Is atherosclerosis a good prognostic precursor of coronary disease?

•The classic cardiac risk scores are based on factors associated with atherosclerosis.•We test atherosclerosis as a mediator between risk scores and cardiac damage.•The more accurate a score is, the less it is mediated by atherosclerosis.•The association with atherosclerosis limits the accuracy of c...

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Bibliographic Details
Main Authors: Lazzarino, Antonio Ivan, Hamer, Mark, Carvalho, Livia, Gaze, David, Collinson, Paul, Steptoe, Andrew
Format: Online
Language:English
Published: Academic Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518041/