Targeted Deletion of Btg1 and Btg2 Results in Homeotic Transformation of the Axial Skeleton

Btg1 and Btg2 encode highly homologous proteins that are broadly expressed in different cell lineages, and have been implicated in different types of cancer. Btg1 and Btg2 have been shown to modulate the function of different transcriptional regulators, including Hox and Smad transcription factors....

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Bibliographic Details
Main Authors: Tijchon, Esther, van Ingen Schenau, Dorette, van Opzeeland, Fred, Tirone, Felice, Hoogerbrugge, Peter M., Van Leeuwen, Frank N., Scheijen, Blanca
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517811/